Screening for Dysglycemia During Postpartum Period in Women With GDM

Recruiting now · Not applicable

Conditions studied: Gestational Diabetes Mellitus (GDM)

In brief

Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood. It is associated with perinatal complications and an increased risk of developing prediabetes and type 2 diabetes after delivery. Therefore, it is recommended that a 75g oral glucose tolerance test (OGTT-75g) be performed between 6 and 12 weeks postpartum. Despite its relevance, the rate of adherence to the test is low. Recent studies also indicate that measuring blood glucose one hour after the overload may be more sensitive than the traditional two-hour measurement in the early detection of dysglycemia. This study aims to evaluate strategies for qualifying the screening of metabolic changes in the postpartum period among women with GDM. The objectives are: (1) to analyze the impact of sending reminders via WhatsApp on the attendance rate for the 75g OGTT; and (2) to compare the frequency of prediabetes and diabetes diagnoses using two different diagnostic strategies applied to the same test-the traditional (fasting and 2-hour blood glucose) and the alternative (fasting and 1-hour blood glucose).

Key facts

Study ID: NCT07489456
Run by: University of Sao Paulo General Hospital
People needed: 182
Starts: 2026-03-24
Expected to finish: 2026-11-01
Last updated by the study team: 2026-05-04

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Diagnosis of gestational diabetes mellitus, according to diagnostic criteria proposed by the IADPSG, namely:
initial fasting blood glucose ≥ 92mg/dL OR
75g oral glucose tolerance test with fasting ≥ 92mg/dL or after 1h ≥ 180mg/dL or after 2h ≥ 153mg/dL Delivery performed at HC-FMUSP Scheduling of the 75g oral glucose tolerance test between 6 and 12 weeks after delivery Agreement with the informed consent form

You may not qualify if…

Withdrawal of consent Failure to complete the TOTG exam due to vomiting (exclusion from analysis 2 only)

Where it is running

University of Sao Paulo General Hospital — São Paulo, São Paulo, Brazil (enrolling)

Full record on ClinicalTrials.gov

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