Remote Ischemic Conditioning for PwSCI

Recruiting now · Not applicable

Conditions studied: Spinal Cord Injuries

In brief

The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI). This pilot study will test the feasibility and acceptability of remote ischemic conditioning implemented in a home setting by persons with SCI and collect cardiometabolic health outcomes to inform appropriate outcomes for a future larger trial. Researchers will compare, RIC high dose using standard blood pressure cuff to RIC high dose using automated blood flow restriction cuff to RIC low dose using standard blood pressure cuff, to determine cardiometabolic health improvements amongst groups. Participants will: Complete an initial 2-day assessment, participate in a 6-week intervention using remote ischemic conditioning (RIC) within their home, complete a 2-day post assessment.

Key facts

Study ID

NCT07488793

Run by

Washington University School of Medicine

People needed

24

Starts

2026-02-23

Expected to finish

2027-07-30

Last updated by the study team

2026-03-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age or older
• Diagnosis of SCI
• Live within the community (not nursing facility)
• Not actively engaged in physical activity for exercise
• Not having the ability to participate in physical activity due to physical capacity or environmental barriers
• Medically stable
• Ability to obtain physician approval to participate in the study
• Willingness to participate in a 2-day initial assessment visit at research testing location, 30 intervention sessions conducted independently by the participant or caregivers, 2-day post intervention assessment visit at research testing location.

You may not qualify if…

• Medically unstable
• Have had a heart-related condition within the past year
• Have had a blood clot in the past year
• Have a stage 3 or 4 pressure injury
• Have taken blood thinners in the past year
• Have had surgery in the past year
• Have uncontrolled hypertension
• Have peripheral artery disease
• Have Complex Regional Pain Syndrome (CRPS) in both arms
• Have had nerve or tendon transfers in the arms in the past year
• Have lymphedema in the arms
• Have recent acute illness or injury (within the past 3 months)
• Currently pregnant
• Enrolled in another clinical trial
• Are taking GLP-1 medications
• Unable to provide consent
• Currently engaged in physical activity for exercise

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States (enrolling)

Full record on ClinicalTrials.gov

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