Language Network Prehab Via fMRI Neurofeedback

Starting soon · Not applicable

Conditions studied: Glioma, Glioma Surgery

In brief

This is an interventional neuroimaging study that will examine whether fMRI neurofeedback can shift language network activity away from regions affected by glioma prior to surgery.

Key facts

Study ID

NCT07488780

Run by

Yale University

People needed

4

Starts

2026-08-01

Expected to finish

2026-12-01

Last updated by the study team

2026-07-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provision of signed and dated informed consent form
• Stated willingness to comply with all study procedures and availability for the duration of the study
• Diagnosis of WHO grade II-III glioma involving eloquent language cortex
• Scheduled for surgical resection
• MRI-compatible
• Ability to perform the simple language tasks required for fMRI and neurofeedback
• Residence within 2 hours of Yale MRRC and ability and willingness to make multiple visits for study participation

You may not qualify if…

• Severe baseline aphasia precluding task performance
• Contraindications to MRI
• Significant cognitive/psychiatric comorbidity limiting compliance
• Concurrent enrollment in other interventional trials
• Claustrophobia of a degree that they cannot comfortably be scanned
• Inability or unwillingness to understand or follow the instructions
• Pregnancy or possible pregnancy

Where it is running

• Yale School of Medicine — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.