Diagnostic Value and Safety of Combined Biopsy for Mediastinal Metastasis of Lung Cancer
Recruiting now · Not applicable
Conditions studied: Mediastinal Metastases of Lung Cancer
In brief
The study is aimed o evaluate the diagnostic performance and treatment guidance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with transbronchial mediastinal cryobiopsy (EBUS-TBMCB) in patients with mediastinal metastases of lung cancer.
Key facts
- Study ID
- NCT07488507
- Run by
- Third Military Medical University
- People needed
- 240
- Starts
- 2026-03-20
- Expected to finish
- 2030-03-01
- Last updated by the study team
- 2026-03-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged ≥18 years;
- Presence of at least one mediastinal lesion (short-axis diameter ≥10 mm) confirmed by thin-slice chest CT;
- Patients who have not undergone prior mediastinal biopsy and require further mediastinal biopsy to confirm etiology or pathological subtype, meeting at least one of the following criterias:
- (1) suspected lung cancer diagnosed by two senior physicians; (2) confirmed lung cancer (requiring mediastinal staging); (3) recurrent lung cancer; 4.Patients must have completed all required preoperative laboratory tests and necessary examinations (e.g., cardiac ultrasound, CTA) to rule out contraindications; 5. Patients are informed and capable of providing written informed consent.
You may not qualify if…
- Presence of severe cardiopulmonary disease, coagulation disorders, massive hemoptysis, poor tolerance to anesthesia, or other contraindications related to bronchoscopy;
- Intraoperative endobronchial ultrasound exploration of the lesion failed to detect the target lesion despite > 20 minutes of attempts;
- Lesions identified as abscesses or cysts;
- Presence of mental illness, severe neurosis, or other conditions that preclude the provision of informed consent;
- Patients who have participated in other clinical trials within 3 months;
- Any other conditions considered to be inappropriate to be involved in this trial.
Where it is running
- Third Military Medical University — Chongqing, Chongqing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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