Efficacy of Structured Progressive Training Exercise on Muscle Strength of Patients With Rheumatoid Arthritis

Starting soon · Not applicable

Conditions studied: Rheumatoid Arthritis (RA)

In brief

This study aims to find out if a specific exercise program helps patients with Rheumatoid Arthritis (RA). RA is a chronic autoimmune disease that causes pain, weakness, and reduced function in the joints and muscles. While medication is common, exercise is also important for management. The study will test a program called "Progressive Resistance Training." About 118 adult patients with RA at AL-Najaf Teaching Hospital will participate. They will be divided into two groups. One group will perform specific resistance exercises for six weeks, while the other group will continue their usual care without this specific training. The researchers will measure muscle strength, cardiovascular function, and energy levels before and after the six-week program. The goal is to determine if this exercise improves muscle strength and helps patients perform daily activities more efficiently. The study hopes to show that resistance training is a safe and effective way to improve quality of life for people with RA.

Key facts

Study ID

NCT07487779

Run by

Kufa University

People needed

118

Starts

2026-04-01

Expected to finish

2026-07-01

Last updated by the study team

2026-04-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with Rheumatoid Arthritis according to American College of Rheumatology criteria
• Age 18-65 years
• Both genders eligible
• Disease duration of at least 6 months
• Stable medication regimen for at least 3 months before study
• Mild to moderate disease activity
• Able to walk independently with or without assistive devices
• Willing and able to provide informed consent
• Agree to participate in the exercise program for 6 weeks
• Attending AL-Najaf Teaching Hospital for RA management

You may not qualify if…

• Severe cardiovascular disease (unstable angina, recent MI, severe heart failure)
• Other inflammatory arthritis (psoriatic arthritis, ankylosing spondylitis, lupus)-
• Recent joint surgery or fracture within the past 6 months
• Severe osteoporosis with fracture risk
• Pregnancy
• Severe cognitive impairment preventing participation
• Uncontrolled hypertension (BP >180/110 mmHg)
• Active infection or fever at baseline
• Severe joint damage preventing exercise participation
• Participation in another exercise program during the study period
• Neuromuscular disorders affecting muscle function

Full record on ClinicalTrials.gov

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