Determination of Clinical Phenotypes of Intrauterine Growth Restriction in Term Infants Based on Body Composition
Enrolling by invitation
Conditions studied: Intrauterine Growth Restriction (IUGR)
In brief
Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to fulfill its genetic growth potential. "Small for gestational age" (SGA) is the most commonly used indicator for diagnosing IUGR. However, this definition does not consider intrauterine growth trajectory or physical characteristics at birth. SGA is based on the relationship between birth weight and gestational age, and does not address anthropometric measurements at birth or prenatal indicators, such as biometric, biophysical, and Doppler velocimetry abnormalities. SGA infants may constitute intrauterine growth restricted as well as constitutionally small infants. This distinction can be made more accurately by complementary assessment of body composition. The clinical meaning of each group identified by body composition will be assessed by the evolution until 3-months of age. The feeding pattern and composition will be considered a major postnatal exposure. Accurate classification of IUGR profiles is essential to ensure appropriate nutritional intervention.
Key facts
- Study ID
- NCT07483424
- Run by
- Centro Hospitalar de Lisboa Central
- People needed
- 290
- Starts
- 2025-11-19
- Expected to finish
- 2028-06-30
- Last updated by the study team
- 2026-04-02
Who can join
Age: 1 and older, up to 1. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- IUGR and term GA (37+0/7 to 41+6/7 weeks of gestation)
You may not qualify if…
- Eligible fetuses with congenital malformations
- Eligible fetuses with genetic mutations.
- Eligible infants with congenital malformations
- Eligible intants with inborn errors of metabolism.
- Infants who become ill and require hospitalization during the study period
- Infants who die during the study period
- Parents or legal guardians who do not agree to participate
- Parents or legal guardians who abandon the study.
Where it is running
- Unidade Local de Saúde São José — Lisbon, Portugal
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.