A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

Recruiting now

Conditions studied: Pulmonary Vascular Disease, Valvular Heart Disease

In brief

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

Key facts

Study ID

NCT07483203

Run by

Mayo Clinic

People needed

600

Starts

2026-04-28

Expected to finish

2028-05-01

Last updated by the study team

2026-06-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥18 years old; AND
• Scheduled for valve procedures

You may not qualify if…

• Congenital heart disease (except for bicuspid aortic valve), OR
• Carcinoid heart disease, OR
• Valvular mass, OR
• Endocarditis, OR
• Any other condition that, in the opinion of the investigator, would impair their ability to complete the study

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.