Tinder Fungus as an Adjunct to Non-surgical Periodontal Therapy for Periodontitis

Starting soon · Not applicable

Conditions studied: Periodontitis

In brief

The goal of this interventional clinical study is to learn if a Tinder fungus-based formulation -specifically a toothpaste and oral supplement powder-works as adjuncts to non-surgical periodontal therapy (NSPT) in patients with periodontitis. The main questions it aims to answer is: • Does the Tinder fungus-based formulation as an adjunct to NSPT reduce bleeding on probing more than a commercially available toothpaste as an adjunct to NSPT? Researchers will compare tinder fungus toothpaste and oral powder as an adjunct to NSPT to a commercially available toothpaste as an adjunct to NSPT to see if the Tinder fungus-based formulation works as adjuncts to NSPT in patients with periodontitis. Participants will: * Take tinder fungus toothpaste and oral powder or a commercially available toothpaste as an adjunct to NSPT twice daily for 30 consecutive days * Visit the clinic at least twice including a visit before and after the intervention * Keep a diary documenting their well-being and the number of times they used the toothpastes in the morning and evening.

Key facts

Study ID

NCT07482878

Run by

Sigmund Freud PrivatUniversitat

People needed

70

Starts

2026-09-01

Expected to finish

2028-12-01

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients diagnosed with Stage III or IV periodontitis
• Patients who have not yet initiated periodontal therapy
• Patients who have at least 20 remaining teeth
• Patients who are willing to use an electric toothbrush
• Patients who are willing to use interdental brushes

You may not qualify if…

• Patients who have previously received treatment for periodontitis
• Patients who have already undergone or initiated periodontal therapy
• Patients with a known allergy or intolerance to any component of the toothpaste or the powder
• Patients who are already using a product that contains tinder fungus (Fomes fomentarius)
• Patients who, at the time of periodontal treatment, are undergoing active systemic cancer therapy (e.g., chemotherapy or immunotherapy) or radiotherapy in the head and neck region, or for whom such therapy is planned. Previous illnesses or completed therapies do not constitute an exclusion criterion, provided that no current or planned treatment exists that could influence the periodontal treatment outcome or pose an increased risk for the participants.

Where it is running

• Dental Clinic of the Sigmund Freud Private University — Vienna, State of Vienna, Austria

Full record on ClinicalTrials.gov

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