Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients

Recruiting now

Conditions studied: Hypotension, Urologic Neoplasms, Aged, Spinal Anesthesia

In brief

Spinal anesthesia-induced hypotension is a common and clinically significant complication in elderly patients undergoing oncologic surgery. Early identification of patients at risk for hemodynamic instability remains a major challenge in perioperative management. Skin conductance reflects sympathetic nervous system activity and may provide a noninvasive indicator of autonomic responses. This prospective observational study aims to evaluate whether skin conductance measurements can predict the development of hypotension following spinal anesthesia in geriatric oncology patients undergoing urologic surgery. The findings may contribute to improved perioperative monitoring and early risk stratification in this vulnerable patient population.

Key facts

Study ID

NCT07481851

Run by

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

People needed

102

Starts

2025-12-22

Expected to finish

2026-05-01

Last updated by the study team

2026-03-25

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 65 years and older
• Patients scheduled for elective urologic oncology surgery under spinal anesthesia
• American Society of Anesthesiologists (ASA) physical status I-III
• Patients who provide written informed consent to participate in the study

You may not qualify if…

• Refusal to participate or inability to provide informed consent
• Contraindication to spinal anesthesia (e.g., infection at puncture site, coagulopathy)
• Severe cardiac conduction abnormalities or presence of a cardiac pacemaker
• Severe autonomic dysfunction or known neuropathy affecting autonomic responses
• Use of medications that significantly affect autonomic nervous system activity
• Baseline hypotension or hemodynamic instability before spinal anesthesia
• Inability to obtain reliable skin conductance measurements (e.g., severe skin lesions at electrode placement site)

Where it is running

• Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea — Ankara, Yenimahalle, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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