Lifestyle Change Implementation Research Network at PRC at UMass Chan

Recruiting now · Not applicable

Conditions studied: GLP - 1

In brief

The goal of this project is to study how well the Noom digital lifestyle program works for adults who are taking Glucagon-Like Peptide-1 receptor agonist (GLP-1) medications. The study team will assess how the program affects people's behaviors and health outcomes. The team will also look at how digital lifestyle change interventions can be implemented in real-world settings, including how many people it reaches, how well it is put into practice, whether people stick with it over time, and whether it works well for different groups of people.

Key facts

Study ID

NCT07481305

Run by

University of Massachusetts, Worcester

People needed

220

Starts

2026-07-22

Expected to finish

2029-09-29

Last updated by the study team

2026-07-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Began using a GLP-1 within the past 6 months
• Currently using GLP-1
• Plans to continue GLP-1 use
• GLP-1 prescribed by their physician (e.g., not online or 3rd party vendor)
• BMI ≥27 kg/m2
• Age 18 years of age and older
• Speaks and reads English or Spanish
• Willing to enroll in a digital lifestyle intervention for 4-months
• Willing to wear a Fitbit for 8 months

You may not qualify if…

• Was taking a GLP-1 within the 2 months prior to the current GLP-1 start date
• Currently participating in a structured lifestyle change program (receiving structured guidance and counseling on physical activity, diet or weight loss)
• Currently pregnant
• Planning to become pregnant in the next year
• Active diagnosis of an eating disorder

Where it is running

• UMass Chan Medical School - Shaw Building — Worcester, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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