Comparison of Platelet-Rich Plasma and Prolotherapy for Plantar Fasciitis

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Conditions studied: Planter Fasciitis

In brief

This randomized controlled trial evaluates the comparative effectiveness of platelet-rich plasma (PRP) therapy and prolotherapy in patients with plantar fasciitis. Both interventions are commonly used regenerative injection therapies intended to improve pain and functional outcomes in patients who do not respond adequately to conventional conservative treatments. Participants diagnosed with plantar fasciitis will be randomly assigned to receive either PRP injection or prolotherapy. The results of this study aim to identify the more effective injection therapy for improving clinical outcomes in patients with plantar fasciitis

Key facts

Study ID

NCT07480967

Run by

Bangladesh Medical University

People needed

68

Starts

2026-04-01

Expected to finish

2027-02-28

Last updated by the study team

2026-03-20

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient with plantar fasciitis not responding to conservative therapy.

You may not qualify if…

• Patients with uncontrolled diabetes, haematological disorders, hepatitis B or C, HIV, clinical signs of acute inflammation, or septicaemia.
• Those receiving local steroid injections within one month.
• Those receiving non-steroidal anti-inflammatory medications within 72 hours.
• Platelet levels 25% below the normal level.
• Patient who had acute ankle or foot trauma, a diagnosis of calcaneal fracture, or stress fracture.

Where it is running

• Bangladesh Medical University — Dhaka, Bangladesh

Full record on ClinicalTrials.gov

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