Comparison of Pain Reduction in Painful Chronic Wounds With and Without Fat Grafting

Starting soon · Not applicable

Conditions studied: Wound and Injuries, Pain

In brief

Chronic wounds, such as those caused by diabetes, burns, or poor blood circulation, often heal slowly and can cause significant pain, affecting daily life and quality of life. This study aims to evaluate whether autologous fat grafting-a procedure in which a patient's own fat tissue is injected into the wound-can reduce pain and improve healing in chronic wounds compared to standard care without fat grafting. We will enroll 62 adult patients with chronic wounds lasting more than 3 months. Participants will be randomly assigned to two groups: one group will receive fat grafting along with standard wound care, and the other group will receive standard wound care alone. Pain will be measured using a Visual Analog Scale (VAS) over 21 days after treatment. Wound healing and any complications will also be monitored. The results of this study will help determine if autologous fat grafting is an effective and safe method to reduce pain and improve recovery in patients with chronic wounds.

Key facts

Study ID

NCT07480447

Run by

King Edward Medical University

People needed

62

Starts

2026-05-01

Expected to finish

2026-11-01

Last updated by the study team

2026-03-18

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• • 3 months old chronic wound (Venous arterial, traumatic, burn and diabetic) having mean VAS Pain score >3 at rest
• Wound area between 4 cm² to 10 cm²
• Aged 20-60 years.
• Both male and female

You may not qualify if…

• • Active wound infection.
• Wounds due to malignancy or irradiation.
• Pregnant or lactating females
• Smokers

Full record on ClinicalTrials.gov

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