mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery
Recruiting now · Not applicable
Conditions studied: Postoperative Pain Management
In brief
The aim of this prospective randomized clinical study is to compare the analgesic efficacy and side effects of modified thoracolumbar interfascial plane block and quadroiliac plane block applied preoperatively in patients undergoing lumbar microdiscectomy surgery.The study will include a total of 80 patients aged 18-65 years with ASA I-III, with 40 patients in each group( Group mTLIP and Group QIPB) undergoing lumbar microdiscectomy surgery. The primary objective of the study is to compare groups in terms of PCA opioid consumption during the 48-hour postoperative period. Secondary objectives are to compare groups in terms of QoR-15 recovery score, dynamic and static numerical rating scale scores, total rescue analgesic use, time to first request for rescue analgesia, length of hospital stay, block and opioid-related side effects and complications, and perioperative remifentanil infusion dose.
Key facts
- Study ID
- NCT07480278
- Run by
- Bursa City Hospital
- People needed
- 80
- Starts
- 2026-03-25
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-03-27
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age between 18 and 65 years
- Classified as American Society of Anesthesiologists physical status I-III
- Scheduled for elective lumbar microdiscectomy surgery under general anesthesia
- Provision of written informed consent
You may not qualify if…
- Use of anticoagulant medications or presence of bleeding diathesis
- Known allergy or hypersensitivity to local anesthetics or opioid drugs
- Infection at the planned block site
- Alcohol or drug dependence
- Cognitive impairment preventing reliable pain assessment
- Pregnancy or lactation
- History of previous lumbar spine surgery
- Diabetes mellitus
- Renal or hepatic insufficiency
Where it is running
- Bursa City Hospital — Bursa, Nilüfer, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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