Transcutaneous pO₂ Monitoring in PICU

Recruiting now

Conditions studied: Pediatric Critical Illness

In brief

Arterial blood gas analysis is commonly used in pediatric intensive care units (PICUs) to assess oxygen and carbon dioxide levels in critically ill children. However, arterial blood sampling is invasive, can be painful, and may need to be repeated frequently. Transcutaneous monitoring provides a noninvasive method to continuously measure oxygen (pO₂) and carbon dioxide (pCO₂) levels through the skin, but its accuracy in critically ill pediatric patients requires further evaluation. The purpose of this observational study is to compare transcutaneous pO₂ and pCO₂ measurements with arterial blood gas values in pediatric intensive care unit patients. By analyzing paired measurements obtained simultaneously during routine clinical care, this study aims to evaluate the agreement between transcutaneous and arterial measurements, with a particular focus on whether transcutaneous pO₂ can serve as a reliable alternative to arterial sampling. The results of this study may help clarify the role of transcutaneous monitoring in pediatric intensive care and may contribute to reducing the need for invasive blood sampling in selected patients.

Key facts

Study ID

NCT07478380

Run by

Istanbul Medeniyet University

People needed

50

Starts

2026-03-10

Expected to finish

2026-10-10

Last updated by the study team

2026-03-17

Who can join

Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 1 month and 18 years
• Admission to the Pediatric Intensive Care Unit (PICU)
• Presence of an arterial catheter allowing arterial blood gas (ABG) sampling
• Simultaneous or paired transcutaneous pCO₂ and pO₂ monitoring available
• Hemodynamically stable at the time of measurement

You may not qualify if…

• Severe skin disease, burns, or local skin infection at the transcutaneous sensor site
• Severe peripheral perfusion impairment (e.g., refractory shock or high-dose vasopressor support)
• Congenital or acquired conditions interfering with accurate transcutaneous measurements
• Technical failure or inability to obtain reliable transcutaneous readings
• Missing or incomplete paired ABG-transcutaneous measurement data

Where it is running

• Göztepe Prof. Dr. Süleyman Yalçın City Hospital — Istanbul, Kadıkoy, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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