Expanded Studies on the SCAPIS Stockholm Reexamination Cohort

Recruiting now

Conditions studied: Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency, Heart Failure, Pulmonary Disease, Chronic Obstructive (COPD), Steatohepatitis, Inflammation Biomarkers, Lipid Profile, Oral Microbiota, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Associated-dysfunction Steatohepatitis (MASH)

In brief

The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018. The study is a collaborative effort among six university hospitals across Sweden. A follow-up study, SCAPIS 2, is conducted for half of the original participants. In Stockholm, 2,500 individuals will be re-examined at Danderyd University Hospital and Karolinska Institutet. SCAPIS 2 includes a core set of examinations involving blood sampling, questionnaires, and imaging. In addition to these, complementary local investigations are conducted to enable more detailed research questions. This protocol describes the additional studies conducted in the Stockholm cohort. All complementary assessments aim to identify risk factors for current and future lung, liver, and cardiovascular diseases.: EXTENDED SAMPLING: Saliva and Blood Samples with Blood Cell Isolation. EXTENDED QUESTIONNAIRES: Dyspnea, Sleep, Respiratory Infections, and Dental Health. EXTENDED IMAGING AND PHYSIOLOGICAL MEASUREMENTS Cardiac Ultrasound and Abdominal Aortic Measurements. Liver Elastography. Vascular Stiffness by cuff-based pulse wave analysis and Photoplethysmography (PPG). Valvular and Vascular Calcification by CT imaging.

Key facts

Study ID
NCT07476703
Run by
Danderyd Hospital
People needed
1400
Starts
2024-04-08
Expected to finish
2026-08-30
Last updated by the study team
2026-03-17

Who can join

Age: 56 and older, up to 74. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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