Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis
Starting soon · Not applicable
Conditions studied: Chronic Knee Osteoarthritis
In brief
The goal of this prospective randomized control trial is to provide continued pain relief, classically long-lasting 3 to12 months, and enhanced function in patients following: both gender; male and female, age group; \>50yr, healthy volunteers along with Radiographic diagnosis of knee OA with KL grade 3 and 4 in addition of Chronic knee pain ≥ 6 months and patients with ≥50% decrease in pain strength after diagnostic genicular nerve block. The main question it aims to answer is: Is ultrasound-guided genicular nerve RFA more efficient in lowering pain intensity at six months contrasted with fluoroscopic guided method in patients with chronic knee osteoarthritis? Researchers will compare Group A (Fluoroscopic) to Group B (Ultrasound) to see comparison in efficiency of ultrasound guided against fluoroscopic guided genicular nerves block for decrease in pain intensity and functional improvement.
Key facts
- Study ID
- NCT07475793
- Run by
- Aga Khan University
- People needed
- 52
- Starts
- 2026-05-01
- Expected to finish
- 2027-05-31
- Last updated by the study team
- 2026-03-27
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Both gender patients of age more than 50 years.
- Radiographic diagnosis of knee OA with KL level 3 and 4.
- Chronic knee pain for more than 6 months
- Patients with more than 50% reduction in pain intensity after diagnostic genicular nerve block
You may not qualify if…
- Lack of consent
- surgery of knee
- Patient with BMI more than 40kg/m2
- Intra-articular steroid injection or hyaluronic acid in last 3 months
- Localized infection at procedure site or knee.
- Patient unable to communicate properly (Severe psychiatric illness, severe dementia and cognitive impairment).
- Patients have moderate to severe low back pain (NRS ≥5)
Full record on ClinicalTrials.gov
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