Safety and Efficacy of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars

Starting soon · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Atrophic Scar

In brief

The purpose of this clinical trial was to evaluate the safety and efficacy of a single administration of TRTP-101 in adults with atrophic scars.

Key facts

Study ID

NCT07474467

Run by

CellinCells

People needed

31

Starts

2026-08-01

Expected to finish

2029-08-01

Last updated by the study team

2026-03-16

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male or Female aged greater than 19 years
• Acne scars graded ≥ 3 on the 5-point ASRS
• [Phase 1]
• Four or more atrophic scars in the joints, genitals, perineum, and face except for the lips, eyes and nose
• [Phase 2]
• Atrophic scar lesions approximately 2 cm in diameter located on the cheeks or temple on both sides of the face
• A response of "dissatisfied" or worse on the Subject Acne Scar Self-Assessment Scale

You may not qualify if…

• History of cell therapy
• Treatment of Dermal resurfacing, Chemical/Mechanical Peel and Skin Photorejuvenation
• Treatment of Hyaluronic acid/collagen skin filler, non-permanent soft tissue filler and fat grafting
• Positive for virus infection
• Use of Anticoagulant therapy or NSAIDs
• Thrombocytopenia or other coagulation disorder
• History of keloid scars
• Infectious disease or other dermatitis in the area of the atrophic scar
• Use of Immunosuppressant, immunomodulating drug, anticancer drug or radiation therapy
• Use of systemic steroid medication
• History of hypersensitivity or severe allergic reactions (e.g., anaphylaxis, Guillain-Barre syndrome, etc.)
• Use of retinoid medications

Where it is running

• Samsung Medical Center — Seoul, South Korea

Full record on ClinicalTrials.gov

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