Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health: A Cross-sectional Analysis.

Starting soon

Conditions studied: Atherosclerosis Cardiovascular Disease, Metabolic Syndrome, Dyslipidaemia, Endothelial Dysfunction

In brief

This study aims to investigate the extent to which vegan or plant-based, omnivorous, and carnivore dietary patterns affect LDL aggregation susceptibility (the affinity for LDL cholesterol particles to clump together in the blood), which may promote plaque build-up in arteries. Using a cross-sectional mixed-methods design, the study will measure LDL aggregation, blood lipids, and other metabolic biomarkers in individuals following these diets, and combine these data with dietary and behavioural information to examine links with cardiovascular and metabolic health.

Key facts

Study ID

NCT07474233

Run by

Liverpool John Moores University

People needed

90

Starts

2026-05-01

Expected to finish

2027-05-01

Last updated by the study team

2026-03-16

Who can join

Age: 25 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults aged 25-60 years.
• BMI range (18.5-29.9 kg/m²).
• Following one of the specified dietary patterns (vegan/plant-based, carnivore, or omnivorous) for a minimum of 6 months.
• Self-identified as health-focused (i.e., intentionally following the diet for perceived health benefits).

You may not qualify if…

• BMI outside the stated range (<18.5 or ≥30 kg/m²).
• Use of lipid-lowering medications or supplements that may interfere with LDL levels.
• Pregnancy or breastfeeding.
• Any significant deviation from the specified diet within the last month.

Where it is running

• Tom Reilly Building, Liverpool John Moores University — Liverpool, ENG, United Kingdom

Full record on ClinicalTrials.gov

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