Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section

Recruiting now · Phase 4

Conditions studied: Infection Control / Methods, Surgical Site Infection (SSI)

In brief

To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.

Key facts

Study ID

NCT07474194

Run by

Beni-Suef University

People needed

150

Starts

2025-09-20

Expected to finish

2026-05-01

Last updated by the study team

2026-03-16

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• female participants with singleton pregnancies scheduled for elective cesarean sections at term, specifically between 37 and 40 weeks of gestation
• free from any medical disorders.
• The participants' ages ranged from 18 to 40 years
• body mass index (BMI) ranged from 18 to 30 kg/m2

You may not qualify if…

• Cases of urgent or emergent CS.
• Abnormal vaginal secretion (bad smelling yellowish secretion, whitish cheesy discharge with pruritus, bloody discharge; etc…).
• Women with medical disorders such as pre-gestational diabetes, anemia, hypertension, preeclampsia, or immunosuppressant pregnant women.
• Women who had a skin infection adjacent to the operative site.
• Allergy to topical povidone-iodine or clindamycin
• Feverish patients or history of premature rupture of membranes or with placenta previa.
• patients lost during follow-up were excluded from the final analysis.

Where it is running

• Beni suef university — Banī Suwayf, Egypt (enrolling)

Full record on ClinicalTrials.gov

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