PET Imaging of MMP Activation in AAA: Clinical Component
Recruiting now · Early Phase 1
Conditions studied: Abdominal Aortic Aneurysm
In brief
A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteristics (WU) with ex vivo tissue measurements (Yale).
Key facts
- Study ID
- NCT07473102
- Run by
- Washington University School of Medicine
- People needed
- 28
- Starts
- 2025-11-03
- Expected to finish
- 2027-03-31
- Last updated by the study team
- 2026-03-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- Washington University School of Medicine — St Louis, Missouri, United States (enrolling)
Full record on ClinicalTrials.gov
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