Impact of Virtual Reality (VR) Based Exercises on Lower Limb Lymphedema Outcomes (LELO)
Recruiting now · Not applicable
Conditions studied: Lymphedema, Gait Dysfunction, Physical Rehabilitation, Chronic Edema
In brief
This randomized controlled study aims to investigate the effects of virtual reality (VR)-assisted gait training, in addition to Complex Decongestive Therapy (CDT), on gait parameters, physical function, quality of life, and edema levels in patients with lower extremity lymphedema. Lymphedema is a progressive condition characterized by the accumulation of protein-rich fluid due to lymphatic drainage insufficiency, leading to chronic inflammation and fibrosis. It impairs gait patterns and reduces functional mobility. VR technologies, such as the RehaWalk system, provide interactive, personalized rehabilitation environments that enhance motor learning, motivation, and adherence to treatment. The study evaluates spatiotemporal gait parameters, three-zone foot analysis (heel, midfoot, forefoot), limb circumferences, ultrasound measurements (dermis, epidermis, subcutaneous fat thickness), and patient-reported outcomes. VR-based training offers a novel, engaging approach to improve physical rehabilitation outcomes in patients with lower limb lymphedema. No significant risks are expected in this study.
Key facts
- Study ID
- NCT07472543
- Run by
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
- People needed
- 40
- Starts
- 2025-09-01
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-03-16
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age between 18 and 65 years
- Diagnosis of unilateral lower extremity lymphedema following gynecological and/or oncological surgery
- Stage 2 or 3 lymphedema
You may not qualify if…
- Decompensated heart, lung, or kidney failure
- Uncontrolled hypertension
- Presence of systemic infection
- Local infections in the lower extremity such as erysipelas or cellulitis
- Venous insufficiency (e.g., deep vein thrombosis)
- Any neuromuscular or orthopedic disease affecting lower extremity walking
- Presence of balance disorders
- Bilateral lymphedema
- Presence of lipolymphedema
- Fracture in the lower extremity
- Active metastasis
- Speech or language problems
- Pregnancy
- Inability to continue treatment (5 days a week for a total of 4 weeks)
Where it is running
- Ankara Gaziler physical therapy and rehabilitationhospital — Ankara, Turkey (Türkiye) (enrolling)
- Gaziler physical therapy and rehabilitation — Ankara, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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