Comparative Study for Facial Scar Remodeling Using Fractional Carbon Dioxide Laser Combined With PDRN Versus Fractional CO₂ Laser
Recruiting now · Phase 2 · Has a placebo group
Conditions studied: Facial Scarring
In brief
Facial scars are frequently deemed unpleasant and can profoundly impact a patient's psychological health. This study compares the effectiveness, safety, and capacity to speed up scar healing in the maxillofacial region between fractional carbon dioxide (CO₂) laser therapy alone and polydeoxyribonucleotide (PDRN) combined with CO₂ laser therapy.
Key facts
- Study ID
- NCT07472192
- Run by
- Misr University for Science and Technology
- People needed
- 36
- Starts
- 2026-03-01
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-03-16
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age Limitations: Participants must be between 18 and 50 years of age.
- Recently cut wounds or surgical scars from about (1-6 months).
- Consent to Participate: Willingness to provide informed consent and engage in all aspects of the study.
You may not qualify if…
- Pregnancy or breastfeeding at the time of study.
- Known allergy to PDRN.
- Medication use that could affect wound healing or inflammation, such as:
- Isotretinoin.
- Anticancer drugs.
- High-dose corticosteroids.
- Anticoagulants.
- Uncontrolled medical diseases (e.g., unstable diabetes, cardiac conditions).
Where it is running
- Misr University for Science and Technology — Giza, Egypt (enrolling)
Full record on ClinicalTrials.gov
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