mexB Efflux Pump Gene Expression, Activity and Biofilm Formation in Clinical Isolates of Pseudomonas Aeruginosa

Starting soon

Conditions studied: Pseudomonas Aeroginosa

In brief

1. Detection of expression level of mexB efflux pump gene in multidrug resistant clinical isolates of Pseudomonas aeruginosa by real time PCR(QRT-PCR). 2. Phenotypic detection of efflux pump activity in multidrug resistant clinical isolates of Pseudomonas aeruginosa. 3. Phenotypic detection of biofilm formation and its degree (strong-moderate-weak) in multidrug resistant clinical isolates of Pseudomonas aeruginosa. 4. Relationship between expression level of mexB efflux pump gene and degree of biofilm formation in multidrug resistant clinical isolates of Pseudomonas aeruginosa.

Key facts

Study ID

NCT07469436

Run by

Assiut University

People needed

80

Starts

2026-04-01

Expected to finish

2028-01-01

Last updated by the study team

2026-03-17

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical isolates confirmed as Pseudomonas aeruginosa by microbiological testing.
• Isolates collected from different clinical specimens (e.g., wound swabs, sputum, urine, blood, and catheters).

You may not qualify if…

• Bacterial species other than Pseudomonas aeruginosa.
• Repeated clinical isolates from the same patient.
• Repeated clinical specimens from different sources of the same patient.

Full record on ClinicalTrials.gov

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