Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder

Starting soon

Conditions studied: Alcohol Use Disorder, Cognition Disorders

In brief

Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations. While many studies have examined AUD from medical and social perspectives, less is known about how individual psychological traits influence the way people with AUD respond to uncertainty and adapt their behavior. This study aims to better understand how personal characteristics such as anxiety, self-esteem, sensitivity to reward and punishment, perfectionism, and cognitive abilities may influence adaptation processes in individuals with AUD. Participants receiving usual care at Paul Brousse Hospital will be invited to take part in a single experimental session lasting about 45 minutes. During this session, they will complete: * A computerized learning task in which they respond to visual stimuli and receive feedback on their performance * Standardized questionnaires assessing psychological traits and cognitive functioning The learning task is designed to evaluate how participants adjust their behavior when the rules of the task change unexpectedly. Researchers will measure how performance changes in response to uncertainty and examine how these changes relate to individual psychological characteristics. This research does not modify participants' medical care and involves no medication or invasive procedures. By improving understanding of the cognitive and behavioral mechanisms involved in Alcohol Use Disorder, the study may help advance scientific knowledge about how individuals adapt to uncertainty and inform future research in addiction and mental health.

Key facts

Study ID

NCT07468825

Run by

Assistance Publique - Hôpitaux de Paris

People needed

30

Starts

2026-04-01

Expected to finish

2027-04-01

Last updated by the study team

2026-03-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18 years or older
• Patients receiving care for Alcohol Use Disorder at the Psychiatry and Addiction Unit of Paul Brousse Hospital
• No objection to participation in the study

You may not qualify if…

• Diagnosed neurological disorder
• Patient covered by State Medical Assistance (AME)
• Individuals under legal protection measures (guardianship, curatorship, or legal safeguard)
• Individuals deprived of liberty by judicial or administrative decision
• Pregnant or breastfeeding women
• Psychiatric disorders that could compromise proper study participation (excluding Alcohol Use Disorder)

Where it is running

• CHU Bicêtre — Le Kremlin-Bicêtre, France

Full record on ClinicalTrials.gov

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