Postnatal Exercise to Activate Baby's Brown Fat
Recruiting now · Not applicable
Conditions studied: Childhood Obesity Prevention, Childhood Obesity, Physical Activity, Lactation, Breastfeeding, Pregnancy, Exercise
In brief
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.
Key facts
- Study ID
- NCT07467694
- Run by
- Joslin Diabetes Center
- People needed
- 200
- Starts
- 2025-12-01
- Expected to finish
- 2030-07-01
- Last updated by the study team
- 2026-03-12
Who can join
Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- 18-45 y of age at the time of enrollment
- Pre-gravid or first trimester BMI 18.5 -40 kg/m2
- Uncomplicated singleton pregnancy
- Intention to exclusively breastfeed for >3 months and, if parity >1, that they successfully breastfed a previous pregnancy
- Term pregnancy (gestational age 37 to <42 weeks)
- Infant with birth weight >10th percentile of weight for gestational age
You may not qualify if…
- Any obstetric contra-indication to exercise at 1 month
- Diagnosis of uncontrolled (HbA1c >7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin
- Intrauterine growth restriction
- Pre-eclampsia or other pregnancy complications
- Alcohol, cannabis or tobacco use
- Known congenital metabolic, endocrine disease, or congenital illness affecting infant feeding/growth
- Major fetal anomalies
- Musculoskeletal issues that would make exercise difficult
Where it is running
- Joslin Diabetes Center — Boston, Massachusetts, United States (enrolling)
- Oklahoma University College of Medicine — Oklahoma City, Oklahoma, United States (enrolling)
Full record on ClinicalTrials.gov
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