Levator Muscle and Its Aponeurotic Maldevelopment in Congenital Ptosis

Starting soon · Not applicable

Conditions studied: Congenital Ptosis

In brief

this study reports the incidence of levator muscle dysgenesis among patients with simple congenital myogenic ptosis. In addition, the study aims to describ the nature of the dysgenesis, including the gross appearance of the muscle intraoperatively as well as the histopathological features under the microscope, correlation between the degree of dysgenesis and the preoperative ptosis assessment, and evaluation of the surgical outcome after levator muscle resection. Also, this research aims to shed light on the role of aponeurotic developmental anomalies, specifically fibrotic changes and maldevelopment in the pathogenesis of simple congenital ptosis.

Key facts

Study ID

NCT07466706

Run by

Assiut University

People needed

153

Starts

2026-04-01

Expected to finish

2028-12-31

Last updated by the study team

2026-03-12

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Unilateral or bilateral simple congenital ptosis

You may not qualify if…

• Previous eyelid or orbital surgery.
• Acquired ptosis (traumatic, myogenic, or neurogenic).
• Complex congenital ptosis (e.g., Marcus Gunn jaw-winking phenomenon, Blepharophimosis syndrome).
• Poor or inverted Bell's phenomenon

Where it is running

• AssiuyU — Asyut, Egypt

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.