Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents
Recruiting now · Not applicable
Conditions studied: Obesity & Overweight, Eating Disorders, Body Image Disturbance, Gender Diverse Populations
In brief
Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities. However, no structured lifestyle interventions specifically tailored to this population have been developed. This randomized controlled trial aims to evaluate the effectiveness of a 6-month interdisciplinary lifestyle intervention designed to prevent obesity and eating disorders in transgender and gender-diverse adolescents aged 10-14 years. Participants will be randomized (1:1) to either an intervention group receiving monthly group sessions (for adolescents and caregivers separately) and weekly supportive messages, or a control group receiving standard outpatient care and general health recommendations. The primary outcome is quality of life measured by the WHOQOL-BREF. Secondary outcomes include eating disorder symptoms, body image, diet quality, physical activity levels, sedentary behavior, body composition, and anthropometric measures.
Key facts
- Study ID
- NCT07466069
- Run by
- University of Sao Paulo
- People needed
- 24
- Starts
- 2026-03-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-03-12
Who can join
Age: 10 and older, up to 14. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Aged 10-14 years
- Self-identified as transgender or gender-diverse
You may not qualify if…
- Current diagnosis of eating disorder requiring specialized treatment
- Severe psychiatric instability
- Cognitive impairment limiting participation
Where it is running
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo — São Paulo, São Paulo, Brazil (enrolling)
Full record on ClinicalTrials.gov
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