STABLE Pilates for Hypermobility

Recruiting now · Not applicable

Conditions studied: Ehlers-Danlos Syndrome (EDS), Hypermobile EDS (hEDS), Hypermobile Spectrum Disorder

In brief

This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.

Key facts

Study ID

NCT07464093

Run by

Brigham and Women's Hospital

People needed

100

Starts

2026-07-01

Expected to finish

2027-12-01

Last updated by the study team

2026-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥ 18 years old;
• Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
• Self-reported persistent pain ≥ 3 months;
• A minimum of 3/10 self-reported pain intensity in the past week
• Able to get on and off the floor without assistance;
• Able to communicate fluently in English; and
• Able to provide written, informed consent

You may not qualify if…

• Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min/week over the past 6 months;
• Recent surgery or acute bone, joint or nerve injury (<6 months);
• Have a history of a severe or progressive neurological or movement disorder;
• Pregnant, planning to become pregnant during the study, or currently breast feeding;
• Unable to get on and off the floor without assistance;
• Unable to complete study procedures due to cognitive impairment;
• Unable to provide written, informed consent; or
• Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.

Where it is running

• Brigham and Women's Hospital — Chestnut Hill, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.