Inflammatory Markers and Clinical Score in Predicting Mortality

Starting soon

Conditions studied: Inflamatory Markers

In brief

To evaluate the prognostic value of inflammatory markers; specifically neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic inflammation immune index (SII) in predicting the severity and outcomes of patients with sepsis, and to compare their predictive accuracy with established clinical scoring systems such as the SOFA (Sequential Organ Failure Assessment) score and APACHE (Acute Physiology and Chronic Health Evaluation) score.

Key facts

Study ID

NCT07464054

Run by

Assiut University

People needed

61

Starts

2026-03-01

Expected to finish

2027-07-01

Last updated by the study team

2026-03-16

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged ≥18 years.
• Admission to ICU with a confirmed diagnosis of sepsis based on current Sepsis-3 criteria.
• Availability of complete baseline laboratory data.

You may not qualify if…

• Patients with hematological malignancies or active chemotherapy. Patients with chronic immunosuppressive therapy (e.g., post-transplant, high-dose corticosteroids).
• Pregnant or lactating women.
• ICU stay less than 24 hours.

Full record on ClinicalTrials.gov

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