Validity and Reliability of Timed Up and Go Test in Dual-Task Conditions for Multiple Sclerosis Patients

Enrolling by invitation

Conditions studied: Multiple Sclerosis, Reliability and Validity, Dual Task

In brief

his study aims to examine the validity and reliability of the Timed Up and Go (TUG) test in patients with Multiple Sclerosis (MS) under dual-task conditions, where participants perform both a motor and a cognitive task at the same time. MS affects movement, balance, and cognitive functions, which can lead to difficulties in walking and increased risk of falls. In this study, volunteers with MS will be asked to perform the TUG test in different conditions: Single-task TUG: walking, standing up, and sitting down without additional tasks. Cognitive dual-task TUG: performing TUG while doing a cognitive task, such as counting backwards or word generation. Motor dual-task TUG: performing TUG while carrying a small object on a tray. Participants' demographic and clinical information will be recorded, and tests will be repeated to evaluate the reliability of the measurements. The results will help determine if the TUG test can reliably assess both motor and cognitive performance in MS patients. The study is observational, and no experimental treatment will be given. Participation involves only performing tests and answering questions, taking approximately 25-30 minutes per session. All collected data will be kept confidential.

Key facts

Study ID

NCT07462338

Run by

Sanko University

People needed

50

Starts

2026-02-15

Expected to finish

2026-04-01

Last updated by the study team

2026-03-10

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with Multiple Sclerosis (MS).
• Age 18 years or older.
• EDSS score low to moderate (able to walk without assistive devices).
• Willing to provide informed consent.
• Able to perform Timed Up and Go (TUG) test.

You may not qualify if…

• Severe cognitive impairment preventing understanding of instructions.
• Recent MS relapse (within the past 30 days).
• Use of walking aids that interfere with TUG test performance.
• Other neurological or musculoskeletal conditions affecting walking or balance.
• Any condition that makes participation unsafe, according to the investigato

Where it is running

• Sanko Unıversıty — Gaziantep, Gaziantep, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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