Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Major Depressive Disorder (MDD)

In brief

POWER project is a randomized, controlled, non-profit study with the primary objective of testing the effectiveness of non-pharmacological interventions-such as physical activity, cognitive training, and dietary supplementation-in reducing depressive symptoms and preventing or delaying cognitive impairments that frequently co-occur in individuals with Major Depressive Disorder (MDD).

Key facts

Study ID

NCT07462013

Run by

National Science and Technology Council, Taiwan

People needed

120

Starts

2025-10-01

Expected to finish

2028-09-01

Last updated by the study team

2026-06-17

Who can join

Age: 50 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 50-80 years old
• Major Depressive Disorder
• Absence or mild cognitive impairment

Where it is running

• Mind Body Interface Research Center (MBI Lab & Care) — Taichung, Taichung, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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