Memory Enhancement in Aging With Optimal Dosing

Recruiting now · Not applicable

Conditions studied: Aging, Noninvasive Brain Stimulation, Memory

In brief

This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free approaches for Alzheimer's disease and related dementia (ADRD). We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen memory-supporting networks.

Key facts

Study ID

NCT07461584

Run by

Boston University Charles River Campus

People needed

240

Starts

2026-06-01

Expected to finish

2031-01-31

Last updated by the study team

2026-07-22

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 65 years of age or older
• normal or corrected-to-normal vision
• color vision

You may not qualify if…

• pregnant
• metal implants in head
• implanted electronic devices
• history of neurological problems or head injury
• skin sensitivity
• claustrophobia
• dementia (normal Montreal Cognitive Assessment > 25)
• depression (normal Geriatric Depression Scale < 10)
• history of psychosis
• cognitive deficits (MoCA>25)
• any psychoactive medication

Where it is running

• 111 Cummington Mall — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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