Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

Recruiting now · Not applicable

Conditions studied: Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)

In brief

To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .

Key facts

Study ID: NCT07461090
Run by: Menoufia University
People needed: 60
Starts: 2026-02-01
Expected to finish: 2027-02-01
Last updated by the study team: 2026-03-11

Who can join

Age: 1 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

American Society of Anesthesiology score 1-3.
Indication for :
Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney
Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery.
Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion.
Patient deemed fit for general anesthesia and surgery.
Patient provides written informed consent.

You may not qualify if…

emergency surgery, dialysis-dependent patients, planned hybrid procedures.
Patients with incomplete data
Patients with metastatic disease at presentation.
Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy.
Need for concomitant major procedures (eg, large bowel resection) at index operation.
Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction.
Uncorrected coagulopathy.
Pregnancy or Obese patient (BMI > 40)
Inability to provide informed consent or comply with follow-up.

Where it is running

Menoufia Faculty of Medicine — Shibīn al Kawm, Shebin Elkom, Egypt (enrolling)

Full record on ClinicalTrials.gov

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