IL-6 and Hemogram-Derived Inflammatory Indices for Mortality Prediction in Postoperative ICU Patients

Recruiting now

Conditions studied: Postoperative Complications, Critical Illness, Inflammation, Intensive Care Unit Admission

In brief

This prospective observational cohort study aims to evaluate the predictive value of interleukin-6 (IL-6) levels and hemogram-derived inflammatory scores for morbidity and in-hospital mortality in postoperative patients admitted to the intensive care unit (ICU). IL-6 levels and inflammatory indices will be assessed at ICU admission and at 24 hours using data obtained from routine clinical care. Associations between these biomarkers and clinical outcomes, including mortality, morbidity, antibiotic use, and duration of mechanical ventilation, will be evaluated after adjustment for illness severity.

Key facts

Study ID

NCT07460141

Run by

Ezgi Günaydın

People needed

42

Starts

2025-12-15

Expected to finish

2026-03-15

Last updated by the study team

2026-03-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Postoperative patients admitted to the ICU
• Availability of complete clinical and laboratory data at ICU admission and at 24 hours
• Provision of informed consent by the patient or legally authorized representative

You may not qualify if…

• Age < 18 years
• Thoracic surgery patients
• Cardiac surgery patients

Where it is running

• Recep Erin — Trabzon, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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