Clinical Performance of a Novel Self-cured Resin Composite Compared to a Light-cured Bioactive Resin Composite Restoration in Proximal Cavities of Posterior Teeth

Recruiting now · Early Phase 1

Conditions studied: Proximal Cavities of Posterior Teeth

In brief

The development of dental caries is multi-factorial mainly due to the presence of 4 elements which are: dental biofilm, fermentable carbohydrates , dental hard tissue and time. Other additional social and environmental factors can have a substantial impact on the onset and course of the disease. Dietary habits, oral hygiene, salivary flow and fluoride exposure are key factors that influence the susceptibility to dental caries. If dental caries is properly managed, it is a preventable and reversible disease. The proximal teeth surfaces are the most susceptible sites for demineralization from the acidic byproducts. In modern restorative dentistry, clinicians always seek solutions that streamline procedures, improve outcomes and reduce chair time for patients. Traditional light-cured composite systems often involve a complex seven step process which includes etching, priming, bonding and curing which consumes from 90 to 120 seconds to be completed. With each additional step, the risk of technique errors increases, potentially compromising the longevity of the restoration. Self-cure composites, with their simplified application process, are emerging as a preferred choice over the traditional seven-step composite materials. Recently, a novel self-cured high-performance bulk-fill restorative material has been introduced into the market (Stela, SDI, Victoria, Australia). It's particularly known for its "unlimited" depth of cure and self-adhesive properties.

Key facts

Study ID: NCT07457749
Run by: British University In Egypt
People needed: 50
Starts: 2026-02-18
Expected to finish: 2028-03-18
Last updated by the study team: 2026-03-19

Who can join

Age: 18 and older, up to 47. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Subjects between the ages of 18-47 years old
Primary caries removal
Good or moderate oral hygiene
Free of periodontal diseases (probing depth and attachment levels within normal limits/ no furcation involvement/ no mobility)
Cooperative patients who agree to keep the scheduled recall appointments for data collection and maintenance

You may not qualify if…

Composite or amalgam removal
Caries extended to the cemento-enamel junction in Class II caries
Grade II or III mobility
Considerable periodontal disease without treatment
Endodontically treated teeth with extensive loss of tooth tissues
Severe wear facets and/or parafunctional activities as clenching or nocturnal bruxism.
Subjects who are pregnant during the duration of the study
Subjects with high caries activity

Where it is running

Faculty of Dentistry, The British University in Egypt — Cairo, El Sherouk City, Egypt (enrolling)

Full record on ClinicalTrials.gov

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