HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke

Recruiting now · Not applicable

Conditions studied: Stroke, Ischemic, Sarcopenia

In brief

The aim of this study is to investigate the effect of post-stroke sarcopenia on prognosis and clinical outcomes in patients with ischemic stroke and to compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MCIT) exercise programs on muscle mass, as well as on functional capacity, quality of life, and clinical outcomes.

Key facts

Study ID

NCT07456956

Run by

Fenerbahce University

People needed

32

Starts

2026-03-02

Expected to finish

2027-06-06

Last updated by the study team

2026-03-25

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• First-ever stroke.
• Age 18 years or older.
• Diagnosis of ischemic stroke.
• Stroke duration between 1-6 months (subacute phase).
• Modified Rankin Scale score < 3.
• Mini-Mental State Examination (MMSE) score ≥ 24.
• Brunnstrom lower extremity motor stage between Stage III-V.
• Lower extremity functional capacity sufficient to allow exercise participation (able to ambulate at least with an assistive device).
• Lower extremity spasticity ≤ 2 according to the Modified Ashworth Scale.
• Independent sitting balance (able to sit unsupported for at least 30 seconds).
• Presence of sufficient voluntary active movement in the lower extremity to permit exercise application.
• Ability to communicate.
• Willingness to participate in the study and provision of written informed consent.

You may not qualify if…

• Presence of hemispatial neglect.
• History of recurrent stroke.
• Presence of a psychiatric disorder.
• Presence of orthopedic, neurological, or cardiopulmonary conditions that would contraindicate the planned exercise protocols.

Where it is running

• Fenerbahçe University — Istanbul, Ataşehir, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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