Prospective Evaluation of Upright Versus Supine CT Myelography of the Lumbar Spine

Enrolling by invitation · Not applicable

Conditions studied: Lumbar Central Canal Stenoses, Neural Foraminal Stenoses

In brief

The purpose of this prospective study is to compare the diagnostic utility of standing (upright, weight-bearing) CT myelography with standard supine CT myelography for the evaluation of lumbar central canal and neural foraminal stenoses. This study aims to determine whether upright positioning provides additional diagnostic information in patients unable to undergo MRI, with the goal of improving assessment and management of degenerative lumbar spine disease.

Key facts

Study ID

NCT07456137

Run by

University of Kansas Medical Center

People needed

20

Starts

2026-06-01

Expected to finish

2026-12-01

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Outpatient status
• Scheduled for routine supine CT myelography

You may not qualify if…

• Inpatient status
• Presence of metallic lumbar spinal hardware
• History of osseous metastatic disease involving the lumbar spine
• Acute traumatic injury involving the lumbar spine
• Pregnancy
• Participant body habitus exceeding the scanner's safe operational limits (e.g., gantry/bore size clearance, table weight capacity) as defined by the device manufacturer.
• Inability to tolerate CT scanning (e.g., severe pain, unable to stand independently for an extended period)

Where it is running

• The University of Kansas Medical Center — Kansas City, Kansas, United States

Full record on ClinicalTrials.gov

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