Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Transcarotid Neuroprotection System

Starting soon

Conditions studied: Extracranial Carotid Artery Disease, TCAR, Transcarotid Artery Revascularization

In brief

The ENTRUST registry's objective is to collect real-world data (RWD) and health economic data on the ENROUTE™ Transcarotid Neuroprotection System (ENROUTE™ Transcarotid NPS), including populations in which outcomes of TCAR in patients with extracranial carotid artery disease are inadequately reported.

Key facts

Study ID

NCT07455747

Run by

Boston Scientific Corporation

People needed

5000

Starts

2026-07-01

Expected to finish

2030-04-01

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient is ≥ 18 years of age*
• Written informed consent (patient data-release form)
• Use of ENROUTE™ Transcarotid Neuroprotection System in conjunction with any commercially available Boston Scientific stent marketed for treatment of carotid artery disease and specified in the Registry Enrollment Guide(s).
• Refer to the Registry Enrollment Guide for details on enrollment restrictions based on patient age

You may not qualify if…

• Life expectancy of < 1 year or patient is unlikely to derive net clinical benefit from carotid revascularization.
• Patient has primary, recurrent or metastatic malignancy and does not have independent assessment of life expectancy of ≥5 years performed by the treating oncologist or an appropriate specialist other than the physician performing TCAR.

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.