Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction

Recruiting now · Not applicable

Conditions studied: Malocclusions, Canine Retraction

In brief

To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial

Key facts

Study ID

NCT07455656

Run by

Al-Azhar University

People needed

16

Starts

2025-08-01

Expected to finish

2027-08-01

Last updated by the study team

2026-03-06

Who can join

Age: 13 and older, up to 20. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion).
• Fully erupted permanent teeth (except third molar).
• Age 13-20 patients.
• No previous orthodontic treatment.
• Good oral and general health.
• No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement.

You may not qualify if…

• Patients with impacted canines.
• Patients with severe crowding.
• Patients with untreated decay or any endodontic lesions.
• Patients with thyroid, parathyroid, or renal and liver disease.

Where it is running

• Orthodontic Outpatient Clinic, Faculty of Dental Medicine, Al-Azhar University — Cairo, Cairo Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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