UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Recruiting now

Conditions studied: Primary Open Angle Glaucoma (POAG)

In brief

Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved. Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed clinically. This observational study aims to evaluate UBM findings after combined deep sclerectomy with trabeculotomy in patients with primary open-angle glaucoma and to correlate these findings with clinical outcomes.

Key facts

Study ID

NCT07454447

Run by

Minia University Hospital

People needed

30

Starts

2025-11-11

Expected to finish

2026-12-01

Last updated by the study team

2026-03-06

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG).
• Patients who underwent combined deep sclerectomy with trabeculotomy.
• Clear media allowing adequate ultrasound biomicroscopy imaging.
• Written informed consent obtained from the patient .

You may not qualify if…

• Secondary glaucomas (e.g., neovascular, uveitic, traumatic, or angle-closure glaucoma).
• Previous glaucoma filtering surgery in the studied eye.
• Coexisting ocular pathology affecting UBM assessment (e.g., severe corneal opacity, scleral pathology).

Where it is running

• Minia University Hospital — Minya, Minya Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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