Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs
Recruiting now · Not applicable
Conditions studied: Cataract
In brief
This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II \[ZCU\], AcrySof IQ Toric, and AT TORBI 709M) after phacoemulsification cataract surgery. Rotation is quantified by registering postoperative retroillumination photographs to the end-of-surgery baseline using iris/scleral landmarks, with follow-up at postoperative day 1, day 3, week 1, week 2, month 1, and month 3. Associations between rotational outcomes and ocular biometric parameters are analyzed using linear mixed-effects models to inform individualized IOL selection and perioperative management.
Key facts
- Study ID
- NCT07453992
- Run by
- Jin Yang
- People needed
- 400
- Starts
- 2025-01-01
- Expected to finish
- 2030-12-31
- Last updated by the study team
- 2026-03-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults aged 18 years or older with age-related cataract scheduled for phacoemulsification cataract surgery.
- Presence of regular corneal astigmatism requiring toric intraocular lens implantation.
- Eligible for implantation of one of the three study toric intraocular lenses based on preoperative evaluation.
- Ability to understand the study procedures and provide written informed consent.
You may not qualify if…
- History of prior ocular surgery in the study eye.
- History of ocular trauma in the study eye.
- Irregular corneal astigmatism or corneal pathology affecting reliable biometric measurement.
- Intraoperative complications, including anterior capsular tear or posterior capsular rupture.
- Inadequate pupillary dilation during surgery or postoperative examinations.
- Evidence of zonular weakness, zonular dialysis, or lens subluxation.
- Active ocular infection or inflammation.
- Any other ocular or systemic condition judged by the investigator to potentially affect intraocular lens stability or study outcomes.
Where it is running
- Eye and ENT hospital of Fudan University — Shanghai, Shanghai Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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