Pre-analytical Processing of Human Samples for Microbiota Analysis Quality

Starting soon · Not applicable

Conditions studied: Healthy

In brief

The goal of this study is to optimise the pre-analytical process for metagenomic analysis of the microbiota in comparison with the current reference technique. A comparative evaluation will be performed between the following and the reference standard (quickly frozen fresh stool): i) faecal sample collection devices commonly used in France and abroad for metagenomics, metabolomics and culturomics; ii) self-collection device that would allows the collection of faecal material and the generation of aliquots for all possible omic assessments for research purposes, including metagenomic analysis, as well as culturomics and faecal transfer to animal models.

Key facts

Study ID

NCT07452965

Run by

University Hospital, Montpellier

People needed

10

Starts

2026-03-01

Expected to finish

2026-07-01

Last updated by the study team

2026-03-05

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and/or female
• Age between 18 and 85 years
• No diagnosed pathology
• Not opposed to following the study procedures

You may not qualify if…

• Ongoing digestive neoplasia or < 5 years
• Digestive surgery with intestinal resection
• Presence of inflammatory bowel disease or other familial gastrointestinal pathology
• Chronic use of laxatives
• Use of antibiotics in the two months prior to inclusion
• Life-threatening conditions in the short term (progressive cancer, unstable heart failure, severe liver, kidney or respiratory failure)
• Chronic psychosis or psychotic episodes
• Alcohol or drug addiction
• Epilepsy and other non-degenerative diseases of the central nervous system
• Vitamin B12 and folic acid deficiency not supplemented
• Untreated hypothyroidism
• Pregnant or breastfeeding woman
• Person deprived of liberty by judicial or administrative decision
• Major protected by law
• Not affiliated with a social security scheme or beneficiary of such a scheme
• Having a period of relative exclusion in relation to another protocol
• Having refused to participate in the protocol

Where it is running

• CHU de Montpellier — Montpellier, France, France

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.