Hesperidin RCT in MS

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Multiple Sclerosis

In brief

This study is a randomised, double-blind, placebo-controlled trial investigating the effects of Hesperidin supplementation on cognitive function, fatigue, and stress. Participants will be randomly assigned to receive either 500mg of Hesperidin or a matching placebo daily for 12 weeks. The primary outcome is fatigue, with secondary outcomes including cognitive performance and mood. The trial seeks to determine if this dietary intervention offers symptom-alleviating benefits.

Key facts

Study ID

NCT07452562

Run by

Swansea University

People needed

60

Starts

2026-01-07

Expected to finish

2027-01-18

Last updated by the study team

2026-03-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Multiple Sclerosis, Aged 18 years or older.

You may not qualify if…

• Known food allergies, intolerances, or significant gastrointestinal (GI) problems, Participants under the age of 18 years.

Where it is running

• FHMLS, Nutrition Lab — Swansea, Wales, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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