Evaluation of Cervical Invasion and Length in Placenta Accreta Patients
Starting soon
Conditions studied: Placenta Accreta Spectrum, Placenta Accreta, Placenta Previa
In brief
Placenta accreta spectrum (PAS), also called morbidly adherent placenta, is a serious pregnancy problem where the placenta attaches too deeply to the uterus wall and does not come out normally after birth. This often happens after previous cesarean sections or when the placenta is low (placenta previa). It can cause heavy bleeding, serious complications, and danger to the mother. This study will look at pregnant women with PAS at Sohag University Hospital in Egypt. Researchers will use ultrasound to check two things: How much the placenta has invaded the cervix (the lower part of the uterus). The length of the cervix. The main goals are to find out: How common cervical invasion is in PAS cases. What happens to women who have this invasion (outcomes like bleeding or surgery needs). If a short cervix is linked to early labor (preterm birth). Women with confirmed PAS will join this observational study from March 2026 to January 2028. They will have extra ultrasound scans during pregnancy. No new treatments or drugs are tested - the study only collects information from routine care and scans to better understand the condition. This research may help doctors predict risks earlier, plan safer deliveries, and improve care for mothers and babies with PAS in the future.
Key facts
- Study ID
- NCT07452185
- Run by
- Sohag University
- People needed
- 200
- Starts
- 2026-03-01
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2026-03-05
Who can join
Age: any. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Pregnant women aged 18-45 years with suspected or confirmed PAS based on prenatal ultrasound (e.g., placenta previa with at least one prior cesarean section).
- Gestational age between 18-32 weeks at enrollment to allow for serial monitoring.
- Singleton pregnancy.
- High-risk features such as history of multiple cesarean sections, antepartum bleeding, or abnormal placental location on initial screening.
You may not qualify if…
- Multiple gestation.
- Pre-existing cervical incompetence or cerclage placement prior to enrollment. -Transfer from outside facilities without complete prenatal records.
Full record on ClinicalTrials.gov
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