Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)
Recruiting now
Conditions studied: Coronary Heart Disease
In brief
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in patients with coronary heart disease (CHD) before and after bypass grafting (cross-sectional study 2).The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CVD, as well as identify new biomarkers for CVD.
Key facts
- Study ID
- NCT07451873
- Run by
- Josip Juraj Strossmayer University of Osijek
- People needed
- 35
- Starts
- 2025-10-01
- Expected to finish
- 2029-09-30
- Last updated by the study team
- 2026-03-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- adult patients of both sexes over 18 years of age
- Caucasian
- undergoing elective coronary artery bypass grafting (CABG)
- provided written informed consent
You may not qualify if…
- emergency surgery
- sepsis or severe systemic inflammation before surgery
- severe renal or hepatic insufficiency
- immunosuppression
- serious comorbidities (e.g., active cancer)
- therapies that could affect oxidative stress (e.g., high doses of corticosteroids)
Where it is running
- Osijek University Hospital — Osijek, Croatia (enrolling)
Full record on ClinicalTrials.gov
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