Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children

Recruiting now · Phase 2

Conditions studied: Small Intestine Bacterial Overgrowth

In brief

The purpose of this Phase IIa study is to identify the most effective antibiotic regimen to treat small intestine bacterial overgrowth (SIBO) in impoverished Bangladeshi children.

Key facts

Study ID

NCT07451171

Run by

University of Virginia

People needed

60

Starts

2026-04-18

Expected to finish

2026-09-01

Last updated by the study team

2026-05-06

Who can join

Age: 1 and older, up to 2. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Positive glucose hydrogen breath test (GHBT)
• Weight-for-age Z score > -1
• Length-for-age Z score > -1

You may not qualify if…

• Presence of known chronic or congenital illness, including developmental delay
• Presence of acute gastrointestinal illness in the preceding 14 days
• Antibiotic use in the preceding 14 days
• Previous adverse reaction to any of the three study medications or other drugs in the same antibiotic classes
• Sibling previously enrolled in this study

Where it is running

• International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) — Dhaka, Bangladesh (enrolling)

Full record on ClinicalTrials.gov

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