The Impact of Saline Temperature and Local Anesthetic Adjuvants on Postoperative Shoulder Pain and Inflammatory Marker Levels Following Laparoscopic Cholecystectomy

Enrolling by invitation · Not applicable

Conditions studied: Shoulder Pain , Laparoscopic Cholecystectomy

In brief

Laparoscopic cholecystectomy has become the gold standard for the operative treatment of gallbladder disease due to its minimally invasive nature and improved patient outcomes. However, postoperative pain remains a significant concern following this procedure, affecting patient comfort, recovery, potential for same day discharge and overall satisfaction. However, visceral pain, port-site pain, and referred shoulder pain are occasionally reported in laparoscopic cholecystectomy patients . Postoperative shoulder pain is a common complication following laparoscopic cholecystectomy, often attributed to diaphragmatic irritation.

Key facts

Study ID

NCT07450781

Run by

Alexandria University

People needed

216

Starts

2026-02-01

Expected to finish

2027-08-01

Last updated by the study team

2026-03-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-65 years.
• Scheduled for elective laparoscopic cholecystectomy
• Informed consent obtained.

You may not qualify if…

• 1 - Allergies to anesthetics or saline. 2-Previous shoulder surgery. 3-Significant comorbidities (e.g., chronic pain syndromes, autoimmune diseases). 4-Pregnancy or lactation.
• 5-Current use of anti-inflammatory medications or steroids

Where it is running

• medical research institute , Alexandrria university — Alexandria, Egypt

Full record on ClinicalTrials.gov

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