Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

Recruiting now · Not applicable

Conditions studied: Chalazion

In brief

This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.

Key facts

Study ID

NCT07450495

Run by

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong

People needed

80

Starts

2025-02-25

Expected to finish

2026-04-01

Last updated by the study team

2026-03-04

Who can join

Age: 1 and older, up to 6. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children aged 1 to 6 years (12-72 months)
• Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia
• American Society of Anesthesiologists (ASA) physical status I
• Assessed as suitable for inhalation anesthesia by anesthesiologists
• Written informed consent obtained from parents or legal guardians

You may not qualify if…

• ASA physical status II or higher
• Known hepatic or renal dysfunction
• Congenital heart disease
• History of malignant hyperthermia
• Known allergy to sevoflurane
• History of asthma or severe respiratory disease
• Upper respiratory tract infection within the past 4 weeks
• Anticipated difficult airway
• Refusal of participation by parents or legal guardians

Where it is running

• Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong — Shantou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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