The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression

Recruiting now · Not applicable

Conditions studied: Varicose Veins, Chronic Venous Insufficiency

In brief

Technically successful laser crossectomy will reduce the risk of reflux recurrence at the sapheno-femoral junction without increasing the risk of endovenous heat-induced thrombosis, which may positively impact the likelihood of ultrasound- or clinical-recurrence of varicose veins. Similar technical efficacy is expected for laser crossectomy at 1940 nm and 1470 nm. A possible advantage of the 1940 nm wavelength in terms of postoperative pain intensity and the risk of adverse events cannot be ruled out.

Key facts

Study ID

NCT07449728

Run by

Pirogov Russian National Research Medical University

People needed

400

Starts

2026-01-20

Expected to finish

2029-01-20

Last updated by the study team

2026-03-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >18 years
• Primary VVs of Clinical Etiology Anatomy Pathophysiology (CEAP) clinical class of C2-C6
• Reflux along the GSV trunk lasting >0.5 sec.
• GSV trunk diameter ≤12 mm
• Informed consent to participate in the study

You may not qualify if…

• Primary reflux outside the GSV trunk (including combined reflux)
• History of deep or superficial vein thrombosis
• Deep vein reflux
• Non-thrombotic or post-thrombotic venous obstruction
• Pelvic venous insufficiency
• Use of oral anticoagulants
• Indication for pharmacological prophylaxis after EVLT
• Inability to use radial fiber of 1.4-1.57 mm at the surgeon's discretion
• Refusal to participate in the study

Where it is running

• MedSwiss Private Cinic — Moscow, Russia (enrolling)

Full record on ClinicalTrials.gov

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