Losartan for Corneal Fibrosis
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Corneal Scarring Fibrosis
In brief
This is a prospective, randomized, double-blinded, controlled clinical trial designed to evaluate the efficacy and safety of topical losartan in improving visual acuity, contrast sensitivity and reducing corneal densitometry, corneal aberrations and corneal scarring severity in adult patients with corneal scars of different etiologies. Participants will be randomly assigned to receive either topical losartan 0.8 mg/mL or placebo eyedrops 6 times per day for six months.
Key facts
- Study ID
- NCT07449000
- Run by
- Universidad Autonoma de Nuevo Leon
- People needed
- 46
- Starts
- 2026-02-12
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-05-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Ophthalmology Department — Monterrey, Nueo Leon, Mexico (enrolling)
Full record on ClinicalTrials.gov
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